# Readings

The table below provides information on the course's lecture (L) and exam (E) sessions.

### Text Readings

All Text Readings are in Dill, K., and S. Bromberg. Molecular Driving Forces. New York, NY: Routledge, 2002. ISBN: 9780815320517.

### Additional References

van Holde = van Holde, K. E., W. C. Johnson, and P. S. Ho. Principles of Physical Biochemistry. Upper Saddle River, NJ: Prentice Hall, 1998. ISBN: 9780137204595.

Eisenberg = Eisenberg, D., and D. Crothers. Physical Chemistry with Applications to the Life Sciences. Menlo Park, CA: Benjamin/Cummings, 1979. ISBN: 9780805324020.

Kittel = Kittel, C., and H. Kroemer. Thermal Physics. 2nd ed. New York, NY: W.H. Freeman, 1980. ISBN: 9780716710882.

SES # | TOPICS | TEXT READINGS | ADDITIONAL REFERENCES
--- | --- | --- | ---
L1 | Introduction Purpose of Stat Mech Probability | Ch. 1 (Ex. 1.1-1.6) |
L2 | Probability | Ch. 1, 2 |
L3 | Equilibrium States | Ch. 2 (Through Ex. 2.2) |
L4 | Equilibrium States – Lattice Model for Diffusion Rubber Elasticity | Ch. 2 |
L5 | Introduction to Conservation Laws (1st Law, Quantization, 2nd Law) | Ch. 3 |
L6 | Boltzmann’s Law and Entropy as an Extensive Property Law of Increased Entropy | Ch. 6 (Through Ex. 6.2) | Kittel, Ch. 2
L7 | More Boltzmann’s Law Partition Functions | Ch. 6 |
L8 | Simulations PCR |  |
E1 | Quiz I |  |
L9 | Thermodynamic Systems Intensive/Extensive Properties Fundamental Equations for Energy and Entropy Definitions of Thermodynamic Driving Forces (Part 1) Thermodynamic Forces Homogeneous Functions Definition of Equilibrium, Temperature, Pressure | Ch. 7 (To Ex. 7.4) |
L10 | Introduction to Chemical Potential - Thermo Cycles - First Law Relations between Heat, Work, Energy | Ch. 7 |
L11 | Reversible and Irreversible Processes | Ch. 7 |
L12 | Introduction to Free Energy Helmholtz Free energy | Ch. 8 |
L13 | Enthalpy Gibbs Free Energy | Ch. 8 | Kittel Problem, 9.4 van Holde, Ch. 2
L14 | Fundamental Equations and their Natural Variables Heat Capacities Equilibrium Temperature | Ch. 8 |
L15 | Thermodynamic Cycles Carnot Cycle and Inequality Heat Engines Path Dependence | Ch. 8 | Kittel, Ch. 8
L16 | Partial Molar Properties | Ch. 9 |
L17 | Partial Molar Properties II | Ch. 9 | Eisenberg, Ch. 7
L18 | Simulations Monte Carlo |  |
E2 | Quiz II |  |
L19 | Boltzmann Distribution Law | Ch. 10 |
L20 | Partition Functions | Ch. 10 |
L21 | Prediction of Thermodynamic Properties from Partition Functions Ensembles | Ch. 10 | Eisenberg, Ch. 14
L22 | Quantum Partition Function | Ch. 10, 11 |
L23 | Equipartition | Ch. 11 |
L24 | Equipartition (cont.) | Ch. 11 |
L25 | Chemical Equlibria Le Chatelier’s Principle (Ex. 8, Pressure Denaturation of Proteins) van’t Hoff | Ch. 13 (To Ex. 13.18) | van Holde, Ch. 3
L26 | Solid-liquid-gas Equilibrium | Ch. 14 |
L27 | Solutions and Mixtures Polymers | Ch. 15, 31 |
L28 | Solvation – Osmotic Pressure | Ch. 16 |
L29 | Solvation – Protein/Macromolecule Adsorption at Interfaces | Ch. 16 | van Holde, Ch. 2
L30 | Polymer Chain | Ch. 31 |
E3 | Quiz III |  |
L31 | Polymer Chain II | Ch. 32 |
L32 | Polymer Chain III | Ch. 33 |
L33 | Cooperativity | Ch. 26 |
L34 | Cooperativity (cont.) | Ch. 28 |
L35 | Protein Folding |  | van Holde, Ch. 2
L36 | Review |  |