# Lecture Notes

## Instructors

MK: Prof. Mehran Kardar
LM: Prof. Leonid Mirny

Lecture notes files.
SES # | TOPICS | INSTRUCTORS
--- | --- | ---
1 | Introduction; Master equation | MK
2 | Elements of population genetics | LM
3 | Evolving populations (forward Kolmogorov) | MK
4 | Population genetics (fitness, selection, ...) | LM
5 | Fixation (backward Kolmogorov) | MK
6 | Introduction to sequence alignment | LM
7 | Algorithms for sequence alignment | LM
8 | Significance of aligments (extreme value distributions) | MK
9 | Ionic interactions | MK
10 | Polymer theory 1, entropy elasticity, collapse | MK
11 | Polymer theory 2, collapse, Random energy model | MK
12 | Protein folding 1: elements of structure and forces | LM
13 | Protein folding 2: evolved (designed) foldable proteins | LM
14 | Protein folding 3: kinetics | LM
15 | Protein folding 4: kinetics | LM
16 | DNA (melting) | MK
17 | RNA (secondary structure) | MK
18 | Protein-DNA interactions 1: specific and non-specific binding | LM
19 | Protein-DNA interactions 2: sequence-dependence & kinetics | LM
20 | Microtubules | MK
21 | Molecular motors & cell motility | MK
22 | Introduction to networks | MK
23 | Dynamics on networks 1 | MK
24 | Dynamics on networks 2 | LM
25 | Packing of DNA inside cells | LM
26 | Cooperativity: hemoglobin and transcription factors | LM